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. 2023 Jan 27;13:1512. doi: 10.1038/s41598-023-28790-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The response of the µIMZI at each stage of the experiment with anti-N Abs used as a receptor and different concentrations of SARS-CoV-2 VLPs. (A) The plot shows the transmission spectra in PBS after incubation and extensive washing; (B) shows resonance wavelength at subsequent steps of SARS-CoV-2 VLP detection for the followed minimum; (C) shows a correlation between the transmission and the wavelength at subsequent steps of SARS-CoV 2 VLPs detection for the followed minimum, as well as for negative control (HNoV VLP). The baseline is indicated with the dashed blue line.