Table 1. NMR Relaxation Measurements of TIA1 LC Domain Aged Liquid Droplets and Seeded Fibrils.
site and sample | 13C T2 (ms) | 15N T2 (ms) |
---|---|---|
bulk, wild-type aged liquid droplet | 2.92 ± 0.01 | 9.80 ± 0.02 |
bulk, P362L aged liquid droplet | 2.93 ± 0.01 | 9.91 ± 0.02 |
bulk, wild-type seeded fibril | 3.22 ± 0.02 | 14.1 ± 0.01 |
sharp signals, wild-type seeded fibrila | 27.4 ± 1.8 | |
broad signals, wild-type seeded fibrila | 10.1 ± 1.1 |
The average of the individual 15N T2 measurements.