TABLE 5.
Preapplications of α7 agonists to wild-type receptors
Drug | HS | n | LS | n | HS vs. LS | HS vs. ACh | LS versus ACh |
---|---|---|---|---|---|---|---|
GTS-21 | 0.064 ± 0.038 | 8 | 0.263 ± 0.122 | 7 | P < 0.05 | P < 0.01 | P < 0.05 |
TC-1698 | 0.012 ± 0.011 | 6 | 0.042 ± 0.028 | 7 | N.S. | P < 0.01 | P < 0.05 |
AR-R17779 | 0.518 ± 0.02 | 7 | 1.002 ± 0.039 | 4 | P < 0.0001 | P < 0.01 | N.S. |
PNU-282987 | 0.800 ± 0.074 | 8 | 0.973 ± 0.137 | 6 | N.S. | P < 0.05 | N.S. |