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. 2023 Feb;103(2):63–76. doi: 10.1124/molpharm.122.000591

TABLE 5.

Preapplications of α7 agonists to wild-type receptors

Drug HS n LS n HS vs. LS HS vs. ACh LS versus ACh
GTS-21 0.064 ± 0.038 8 0.263 ± 0.122 7 P < 0.05 P < 0.01 P < 0.05
TC-1698 0.012 ± 0.011 6 0.042 ± 0.028 7 N.S. P < 0.01 P < 0.05
AR-R17779 0.518 ± 0.02 7 1.002 ± 0.039 4 P < 0.0001 P < 0.01 N.S.
PNU-282987 0.800 ± 0.074 8 0.973 ± 0.137 6 N.S. P < 0.05 N.S.