Table 3.

Inferential analysis 6MWT

	Value	SE	DF	t-value	p-value
Baseline_m14 vs. m14_m26	9.810	4.216	700	2.327	0.02
Baseline_m14 vs. m26_m38	3.155	6.598	700	0.478	0.63
Age at symptom onset	0.034	0.034	146	0.982	0.33
Walking distance at baseline	–0.044	0.017	146	–2.660	0.01
Age at start of treatment	0.011	0.015	146	0.704	0.48
SMN2 copy number	–17.901	5.875	146	–3.047	0.003
Sex M	–2.683	5.656	146	–0.474	0.64
Fatigue	–6.894	3.574	700	–1.929	0.05

Inferential analysis evaluates the effect of age at diagnosis, age at start of treatment, SMN2 copy number (≤3 SMN2 copies vs.≥4 SMN2 copies), gender, baseline 6MWT, and past time from baseline on changes in 6MWT. *Standard error = SE; degree of freedom = DF.