Table 1.

Selection criteria for newborn screening follow-up centers

1) Possibility to offer a consultation appointment within 4 working days at the neuromuscular center

2) Close cooperation with a genetic laboratory in order to get genetic confirmation including determination of SMN2 copy number within 1 week after collection of the control blood sample

3) Ability to perform electroneurography (and electromyography)

4) Pediatric neurologist with experience in the field of SMA (treatment of a minimum of 20 patients within the last 2 years)

5) Personal experience with all currently available SMA specific treatments (nusinersen, risdiplam, onasemnogene-abeparvovec) in order to be able to advice the parents

6) Availability of physiotherapists with training in neuromuscular tests (HINE, CHOP-INTEND, HMFSE, time function tests, 6-min-walk test) to evaluate the outcome of the children

7) Availability of psychological and social support