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. 2022 Jun 29;20(8):1479–1497. doi: 10.2174/1570159X19666210915122820

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© 2022 Bentham Science Publishers

This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

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Fig. (3) — BDNF affects neuronal plasticity, survival, and nerve growth through PLC-γ, PI3K, and MAPK signaling pathways. Abbreviations: (BDNF: brain-derived neurotrophic factor, proBDNF: brain-derived neurotrophic factor precursor, PLC-γ: phosphatase C-γ, PI3K: phosphatidylinositol 3-kinase, MAPK: mitogen-activated protein kinase, AKT: protein kinase B, ERK: extracellular signal-regulated kinase, IP3: inositol 1,4,5-trisphosphate, TrkB-FL: full-length tyrosine kinase receptor B, TrkB-T1: truncated tyrosine kinase receptor B, P75NTR: P75 neurotrophin receptor).