Figure 3.

Comparative benchmarking of CYCLeR and comparable tools. Bar plot of sensitivity precision and F score of CYCLeR and different existing tools based on the simulated reference dataset. The superior F score for CYCLeR shows a good balance between sensitivity and precision. CYCLeR outperforms CIRI-full on all metrics. CIRCexplorer2 matches the sensitivity of CYCLeR, but the number of false positive assemblies shown by the precision measure makes CIRCexplorer2 an unreliable choice. Please also note that CYCLeR output is only marginally affected by the library read length.