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. 2023 Jan 10;9:1040259. doi: 10.3389/fnut.2022.1040259

TABLE 1.

List of extraction methods for bioactive compounds in turmeric.

Extraction method Conditions Curcumin yield References
Conventional solvent extraction Solid/solvent ratio: 1:6 g/g for 12 and 24 h at 50°C 69.1% (31)
Soxhlet extraction Sample amount: 15 g in acetone at 60°C for 8 h 6.9 g curcumin/100 g sample (30, 32)
10 g sample in 250 mL of ethanol for 8 h 1.3 g curcumin/100 g sample
Ultrasound- assisted extraction Solid/solvent ratio: 1:20 g/mL; solvent: acetone for 40 min at 40°C 3.9 g curcumin/100 g sample (30, 32)
Solid/solvent ratio: 1:3 g/L in acetone for 5 min 71.4%
Solid/solvent ratio 1:15–1:55; time: up to 1 h; solvent: ethanol, methanol, acetone, and ethyl acetate at 25–55°C 72%
Microwave- assisted extraction Solid/solvent ratio: 1:20 g/mL; in acetone for 0.5–3 min 2.4 g curcumin/100 g sample (30, 34)
Solid/solvent ratio: 1:3 g/L; in ethanol, acetone, water for 1–7 90%
Subcritical water extraction Sample amount: 0.1 g; flow rate: 0.5 mL/min; 5.0 MPa; temperature: 180, 200, and 220°C; and pH: 1, 1.5, and 2 1.35 g curcumin/100 g (33, 35)
Flow rate: 1, 2.5, and 4 mL/min; temperature: 90, 120, and 150°C; and particle size: 0.5, 1, and 1.5 mm 90%
Particle size: 0.6,0.71, 1, and 2 mm; temperature: 120–160°C; time: 6, 10, 14, 18, and 22 min 76%
Supercritical carbon dioxide 10 g sample in ethanol, time: 240 min; pressure: 30 MPa; temperature: 50°C; flow rate 5 mL/min (34)