Resource Table.

Unique stem cell lines identifier	SCVIi063-A SCVIi064-A
Institution	Stanford Cardiovascular Institute, SCVI
Contact information of distributor	Dr. Joseph C. Wu (joewu@stanford.edu)
Type of cell lines	iPSCs
Origin	Human
Additional origin information	SCVIi063-A; 54-year-old female; Ethnicity: White SCVIi064-A; 44-year-old male; Ethnicity: Other
Cell Source	Blood
Clonality	Clonal
Method of reprogramming	Integration-free Sendai virus expressing human OCT4, SOX2, KFL4, and c-MYC
Evidence of the reprogramming transgene loss	RT-qPCR
Multiline rationale	Non-isogenic cell lines obtained from two patients with heterozygous mutations in HCN4 gene
Gene modification	Yes
Type of modification	Spontaneous mutation
Associated disease	Dilated cardiomyopathy (DCM, OMIM: 115200)
Gene/locus	HCN4 (15q24.1)
	SCVIi063-A: Heterozygous; HCN4; c.2587G > T SCVIi064-A: Heterozygous; HCN4; c.2846G > A
Method of modification	N/A
Name of transgene or resistance	N/A
Inducible/constitutive system	N/A
Date archived/stock date	1. SCVIi063-A (04/11/2020) 2. SCVIi064-A (11/12/2020)
Cell line repository/bank	1. https://hpscreg.eu/cell-line/SCVIi063-A 2. https://hpscreg.eu/cell-line/SCVIi064-A
Ethical approval	The generation of the lines was approved by the Administrative Panel on Human Subjects Research (IRB) under IRB #29904 “Derivation of Human Induced Pluripotent Stem Cells (Biorepository)”.