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. 2023 Jan 13;10:1082183. doi: 10.3389/fpubh.2022.1082183

Table 1.

Projected number of adults 50 years and older with chronic disease in the United States.

Age cohort 2020 2035 2050 Relative change between 2020 and 2050 (%)
Population (million)
Total adult population 137.25
[135.64–139.18]
180.40
[175.17–186.85]
221.13
[213.24–231.34]
61.11%
[57.21% to 66.22%]
50–59 years 48.318
[48.212–48.419]
55.755
[55.634–55.870]
68.555
[68.401–68.700]
41.88%
[41.88% to 41.89%]
60–79 years 72.001
[71.212–72.910]
94.610
[92.326–97.129]
112.40
[109.69–115.39]
56.11%
[54.04% to 58.27%]
80 and older 16.935
[16.148–17.863]
30.042
[26.998–33.875]
40.181
[34.881–47.272]
137.267%
[116.0% to 164.6%]
1 chronic condition (million)
Adult population 71.522
[69.065–73.781]
114.48
[108.87–121.36]
142.66
[134.74–153.39]
99.5%
[95.1% to 107.9%]
50–59 years 15.929
[15.181–16.460]
17.688
[16.820–18.305]
22.277
[21.192–23.047]
39.85%
[39.59% to 40.01%]
60–79 years 44.881
[43.462–46.090]
70.752
[67.520–73.550]
83.511
[79.670–86.834]
86.07%
[83.31% to 88.40%]
80 and older 10.711
[10.012–11.662]
26.040
[23.190–29.936]
36.875
[31.757–44.038]
244.3%
[217.2% to 277.6%]
Multimorbidity (million)
Adult population 7.8304
[6.5965–9.4853]
12.085
[9.6091–15.490]
14.968
[11.813–19.277]
91.16%
[79.09% to 103.24%]
50–59 years 1.6234
[1.3501–1.9254]
1.7968
[1.4913–2.1314]
2.2662
[1.8802–2.6889]
39.6%
[39.26% to 39.66%]
60–79 years 4.9258
[4.1510–6.0167]
7.4836
[5.8964–9.7171]
8.8249
[6.9446–11.454]
79.16%
[67.30% to 90.39%]
80 and older 1.2812
[0.9838–1.5817]
2.8050
[1.9896–3.8781]
3.8777
[2.6510–5.5552]
202.7%
[169.5% to 251.2%]
Prevalence of ≥1 chronic condition (%) 21.77
[21.05–22.37]
34.66
[33.36–36.04]
47.81
[46.09–49.71]
119.7%
[118.9% to 122.2%]
Fraction female 52.57
[51.77–53.20]
53.37
[52.43–54.62]
53.22
[52.07–54.88]
1.25%
[0.57% to 3.16%]
Fraction male 47.43
[46.80–48.23]
46.63
[45.38–47.57]
46.78
[45.12–47.93]
−1.39%
[−3.59 to −0.61%]
Prevalence of multimorbidity (%) 2.383
[2.007–2.887]
3.659%
[2.905–4.696]
5.017
[3.948–6.481]
110.5%
[96.7% to 124.5%]
Fraction female 48.33
[44.71–52.14]
49.40
[44.54–55.21]
49.29
[44.21–55.57]
1.98%
[−1.10% to 6.59%]
Fraction male 51.67
[47.86–55.29]
50.60
[44.79–55.46]
50.71
[44.43–55.79]
−1.86%
[−7.18% to 0.89%]