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. 2023 Jan 13;10:1082183. doi: 10.3389/fpubh.2022.1082183

Table 5.

Projected number of other adults 50 years and older with chronic disease (in millions by sex and age) in the United States.

Age cohort 2020 2035 2050 Relative change between 2020 and 2050 (%)
1 chronic disease (million)
50–59 years 1.0999
[0.9828–1.1846]
1.2283
[1.0907–1.3279]
1.5519
[1.3788–1.6769]
41.10%
[40.29%−41.56%]
60–79 years 3.0872
[2.8448–3.3042]
4.8468
[4.2676–5.3310]
5.7521
[5.0644–6.3334]
86.32%
[78.02%−91.68%]
80 and older 0.7201
[0.5662–0.8631]
1.7029
[1.1205–2.3582]
2.3800
[1.4159–3.6244]
230.5%
[150.1%−319.9%]
Total 4.9072
[4.3938–5.3519]
7.778
[6.4788–9.0171]
9.684
[7.8591–11.6347]
97.34%
[78.87%−117.4%]
Female
50–59 years 0.5487
[0.4836–0.5946]
0.6086
[0.5328–0.6619]
0.7583
[0.6642–0.8245]
38.19%
[37.33%−38.66%]
60–79 years 1.5952
[1.4542–1.7136]
2.5305
[2.2494–2.7866]
2.9676
[2.6363–3.2725]
86.03%
[81.28%−90.97%]
80 and older 0.4340
[0.3396–0.5224]
1.0081
[0.6614–1.3750]
1.4154
[0.8355–2.1206]
226.1%
[146.1%−305.9%]
Male
50–59 years 0.5511
[0.4992–0.5923]
0.6198
[0.5579–0.6688]
0.7936
[0.7146–0.8560]
43.99%
[43.16%−44.51%]
60–79 years 1.4920
[1.3693–1.5906]
2.3163
[2.0182–2.5507]
2.7844
[2.4282–3.0656]
86.63%
[77.33%−92.73%]
80 and older 0.2861
[0.2266–0.3423]
0.6948
[0.4591–0.9844]
0.9646
[0.5804–1.5037]
237.2%
[156.2%−339.3%]
Multimorbidity (million)
50–59 years 0.1103
[0.0614–0.1523]
0.1231
[0.0693–0.1695]
0.1555
[0.0871–0.2146]
40.98%
[41.78%−40.89%]
60–79 years 0.3176
[0.1315–0.4941]
0.4458
[0.1377–0.8072]
0.5289
[0.1653–0.9555]
66.51%
[2.74%−93.39%]
80 and older 0.0840
[0.0304–0.1709]
0.1584
[0.0335–0.4794]
0.2083
[0.0369–0.7504]
148.0%
[21.5%−339.1%]
Total 0.5119
[0.2233–0.8173]
0.7273
[0.2405–1.4561]
0.8927
[0.2893–1.9205]
74.39%
[29.56%−134.9%]
Female
50–59 years 0.0498
[0.0270–0.0723]
0.0552
[0.0301–0.0800]
0.0688
[0.0373–0.0999]
38.01%
[38.28%−38.12%]
60–79 years 0.1493
[0.0611–0.2508]
0.2125
[0.0635–0.4316]
0.2487
[0.0749–0.5054]
66.63%
[22.70%−101.5%]
80 and older 0.0478
[0.0172–0.0957]
0.0890
[0.0185–0.2656]
0.1175
[0.0201–0.4220]
145.9%
[16.7%−341.1%]
Male
50–59 years 0.0605
[0.0345–0.0807]
0.0678
[0.0392–0.0910]
0.0867
[0.0498–0.1165]
43.42%
[44.52%−44.43%]
60–79 years 0.1683
[0.0704–0.2506]
0.2332
[0.0742–0.4081]
0.2801
[0.0904–0.4886]
66.41%
[28.38%−94.96%]
80 and older 0.0362
[0.0132–0.0752]
0.0695
[0.0150–0.2137]
0.0908
[0.0168–0.3283]
150.8%
[27.8%−336.5%]