Table 1: Some special clinical and laboratory findings regarding the presentation of Wilson’s disease .

Features	Asymptomatic 19	Acute 6	Chronic 18	Fulminant 12	Neurological 9	Total	P
	N (%)	N (%)	N (%)	N (%)	N (%)	N (%)
Kayser-Fleischer ring	4 (21)	2 (33.3)	9 (50)	2 (16.6)	9 (100)	26 (40.6)	0.00
Hemolytic anemia	0 (0)	0 (0)	2 (11.1)	7 (58.4)	0 (0)	9 (14)	0.00
Hypouricemia	5 (26.3)	1 (16.6)	14 (77.8)	12 (100)	5 (55.6)	37 (57.8)	0.00
Low albumin	3 (15.8)	2 (33.3)	11 (61.1)	11 (91.7)	1 (11.1)	28 (43.7)	0.00
High INR	3 (15.8)	0 (0)	14 (77.8)	12 (100)	3 (33.3)	32 (50)	0.00
High ammonium	0 (0)	0 (0)	5 (27.8)	12 (100)	0 (0)	17 (26.5)	0.00
Low HDL	5 (26.3)	1 (16.6)	12 (66.7)	10 (83.4)	4 (44.5)	32 (50)	0.03
Normal ceruloplasmin	2 (10.5)	1 (16.6)	3 (16.6)	0 (0)	1 (11.1)	7 (11)	0.41
Hepatosteatosis (n = 57) (USG)	2/15 (13.3)	4/6 (66.6)	0/17 (0)	1/11 (9)	0/8 (0)	7/57 (12.3)	0.00
Brain involvement (n = 41) (MRI)	1/6 (16.6)	0 (0)	11/14 (79)	5/8 (62.5)	9/9 (100)	26/41 (63.4)	0.00
Steatosis in biopsy (n = 20)	4/5 (80)	2/3 (66.6)	0/4 (0)	1/7 (14.3)	0/1 (0)	7/20 (35)	0.02
Iron accumulation in biopsy (n = 20)	0/5 (0)	0/3 (0)	2/3 (66.6)	3/7 (43)	0/1 (0)	5/20 (25)	0.11
Family history	14 (87.5)	3 (50)	6 (33.3)	4 (33.3)	5 (55.5)	32 (50)	0.103
Detected through screening	13 (68.4)	0	1 (5.5)	0	2 (16.7)	16 (25)	0.000
Hepatomegaly	3 (15.7)	4 (66.7)	17 (94.5)	10 (83.4)	2 (22.3)	36 (56.2)	0.000
Splenomegaly	1 (5.2)	1 (16.7)	15 (83.4)	9 (75)	3 (33.3)	29 (45.3)	0.000
Ascites	0	1 (16.7)	9 (50)	7 (58.3)	2 (22.3)	19 (29.6)	0.002
Jaundice	0	3 (50)	14 (77.8)	12 (100)	0	29 (45.3)	0.000
Encephalopathy	0	0	0	12 (100)	0	12 (18.7)	0.000

INR = international normalized ratio; HDL = high-density lipoprotein; USG = ultrasonography; MRI = magnetic resonance imaging.