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. Author manuscript; available in PMC: 2023 Jan 27.
Published in final edited form as: Breast Cancer Res Treat. 2021 Oct 22;191(1):177–190. doi: 10.1007/s10549-021-06418-x

Table 1.

Study population characteristics for women with breast cancer with or without preoperative MRI1,2.

No MRI (N, %) MRI (N, %)
Overall Overall
Total N = 19,324 13,869 (72.0 %) 5,455 (28.0%)
Age At Exam (years)
 <50 2529 18.2 1521 27.9
 50–59 3401 24.5 1599 29.3
 60–69 3930 28.3 1472 27.0
 70–79 2771 20.0 714 13.1
 80–89 1238 8.9 149 2.7
Race (NCI Reporting Standard)
 White, non Hispanic 10366 76.1 4057 75.5
 Black, non Hispanic 1382 10.1 594 11.1
 Asian 1260 9.2 404 7.5
 Non-Hispanic Pacific Islander,
Alaska Native, American Indian		 68 0.5 27 0.5
 Hispanic 550 4.0 292 5.4
 Other, Mixed, Unknown 243 1.8 81 1.5
First Degree Family History of Breast Cancer
 No 9974 76.5 3890 75.8
 Yes 3062 23.5 1242 24.2
 Unknown 833 6.0 323 5.9
Previous biopsy/aspiration
 None 8463 65.9 2925 61.9
 Biopsy Only 2856 22.2 1320 27.9
 Aspiration Only 615 4.8 224 4.7
 Biopsy and Aspiration 904 7.0 259 5.5
 Unknown 1031 7.4 727 13.3
Menopause
 Pre 2847 23.1 1660 35.3
 Post 9460 76.9 3047 64.7
 Unknown 1562 11.3 748 13.7
Current hormone therapy use
 No 9146 95.4 3566 96.2
 Yes 436 4.6 141 3.8
 Unknown 4287 30.9 1748 32.0
Laterality of index biopsy2
 Left 6770 48.8 2683 49.2
 Right 6936 50.0 2724 49.9
 Bilateral 163 1.2 48 0.9
Index biopsy2 year
 2005–2008 4532 32.7 591 10.8
 2009–2011 3395 24.5 1425 26.1
 2012–2014 3447 24.9 1812 33.2
 2015–2017 2495 18.0 1627 29.8
Geo coding education
  <=Q1 3324 26.1 1288 25.8
  Q1 – Q2 3515 27.6 1228 24.6
  Q2 – Q3 3296 25.9 1393 27.9
  > Q3 2593 20.4 1075 21.6
  Unknown 1141 8.2 471 8.6
Index biopsy2
 DCIS 3103 22.4 1049 19.2
 Invasive3 10766 77.6 4406 80.8
Mode of Detection4
 Screen Detected 8754 64.3 3178 59.1
 Interval Detected 2759 20.3 1303 24.3
 Clinically Detected 2102 15.4 892 16.6
 Unknown Mode 254 1.8 82 1.5
Breast Density
 Almost entirely fat 1442 10.4 284 5.2
 Scattered fibroglandular 5996 43.2 1745 32.0
 Heterogeneously dense 5347 38.6 2622 48.1
 Extremely dense 1084 7.8 804 14.7
Histology Type
 DCIS 3103 28.8 1049 23.5
 Invasive, Ductal 6741 62.5 2813 63.1
 Invasive, Lobular 733 6.8 521 11.7
 Invasive, Ductal & Lobular 210 1.9 73 1.6
 Unknown 3082 22.2 999 18.3
Surgery Type
 Lumpectomy 9787 70.6 3250 59.6
 Mastectomy 4082 29.4 2205 40.4
All 13869 5455
1

Preoperative MRI was defined as any MRI completed between index biopsy and the definitive surgery

2

Index biopsy was defined as the biopsy associated with the pathologically-determined breast cancer diagnosis of invasive breast cancer or ductal carcinoma in situ.

3

Invasive cancer includes lobular invasive, ductal invasive, and other invasive.

4

Mode of detection is as follows: Screen detected: cancer detected within 12 months of a positive screening mammogram; Interval detected: cancer detected cancer within 27 months of a prior negative screening exam; Clinically detected: Cancer detected on a diagnostic exam with no mammogram in prior 27 months.