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[Preprint]. 2023 Jan 12:2023.01.07.523111. [Version 2] doi: 10.1101/2023.01.07.523111

Figure 1: RNA expression in platelets and whole blood of MPN patients and protein expression in platelets.

Figure 1:

(A) MPN Platelet RNA-seq normalized expression data: MPN patients (total n=99: ET n=24; PV n=33; MF n=42) vs healthy donors (n=21) (B) whole blood RNA: MPN patients (total n=109: ET n=39; PV n=38; MF n=32) vs healthy donors (n=10) (C) platelet protein: peripheral blood platelets were isolated from MPN patients (total n=38: MF n=12; PV n=19; ET n=7) and healthy donors (n=11). Bonferroni multiple comparisons adjusted p values ****p<0.0001, ***p<0.001 and **p<0.01 when compared with controls (healthy donors). All RNA expression is normalized to GAPDH and expressed as log2 fold change.