Table 1:

Summary of all cell types used, their sources and the respective analyses performed.

Table 1: Experimental Framework and Components
#	Cell type	Source	Megakaryocyte (MK) culture	ENKUR silencing	ER stress induction	RNA expression (MK and/or Platelet)	Protein expression (MK and/or Platelet)
1	Platelets	Peripheral blood (n = 49)				X CALR, CREB3L1, CDC20, ENKUR	X CALR, CREB3L1, CDC20, ENKUR
2	CD34+	Bone marrow (n = 8)	X			X CALR, CREB3L1, CDC20, ENKUR
3	CD34+	Cord blood (n = 4)	X	X		X CALR, CREB3L1, CDC20, ENKUR	X CALR, CREB3L1, CDC20, ENKUR, PI3K and Akt
4	CD34+	Peripheral blood (n = 7)	X	X	X	X CALR, CREB3L1, CDC20, ENKUR	X CALR, CREB3L1, CDC20, ENKUR, PI3K and Akt