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[Preprint]. 2023 Jan 10:2023.01.09.523303. [Version 1] doi: 10.1101/2023.01.09.523303

Fig. 2: Seeding properties of tissue-derived and amplified fibrils in HEK 293 biosensor cells expressing A53T Asyn-CFP/YFP.

Fig. 2:

Fluorescence images show cells seed with: a, LBD-Insoluble fraction. b, MSA-insoluble fraction. c, LBD-amplified fibrils. d, MSA-amplified fibrils. e, LBD-tissue soluble fraction. f, MSA- tissue soluble fraction. g, LBD-amplified fibrils soluble fraction. h, MSA-amplified fibril soluble fraction. Similar results were observed in more than three independent experiments examining amplified fibrils derived from caudate samples for three cases of LBD and three cases of MSA.