Table 1.
Participant characteristics by SARS-CoV-2 status at enrollment
| SARS-CoV-2 Status at Enrollment | ||||
|---|---|---|---|---|
|
|
||||
| Negative | Positive | All | P-value1 | |
|
|
||||
| Total (row percent) | 1122 (71%) | 455 (29%) | 1577 | |
| Age (Years) | 0.19 | |||
| Mean (SD) | 42 (16) | 43 (15) | 43 (16) | |
| Median (IQR) | 40 (30, 56) | 41.0 (31, 53) | 40.0 (30, 55) | |
| 18–49 | 741 (66) | 314 (69) | 1055 (67) | |
| 50–64 | 247 (22) | 101 (22) | 348 (22) | |
| ≥65 | 134 (12) | 40 (9) | 174 (11) | |
| Sex | 0.15 | |||
| Female | 726 (65) | 277 (61) | 1003 (64) | |
| Male | 396 (35) | 178 (39) | 574 (36) | |
| Race and Ethnicity 2 | 0.09 | |||
| White | 779 (69) | 288 (63) | 1067 (68) | |
| Black | 57 (5) | 26 (6) | 83 (5) | |
| Hispanic | 173 (15) | 81 (18) | 254 (16) | |
| Asian | 96 (9) | 46 (10) | 142 (9) | |
| Other/unknown | 17 (2) | 14 (3) | 31 (2) | |
| Self-Reported Chronic Medical | 0.24 | |||
| Condition 3 | ||||
| Yes | 324 (29) | 118 (26) | 442 (28) | |
| No | 798 (71) | 337 (74) | 1135 (72) | |
| High-Risk SARS-CoV-2 Exposure 4 | <0.01 | |||
| Yes | 413 (37) | 230 (51) | 643 (41) | |
| No | 709 (63) | 225 (50) | 934 (59) | |
| Highest level of education5 obtained | 0.52 | |||
| High school or less | 188 (17) | 83 (18) | 271 (17) | |
| College | 690 (62) | 280 (62) | 970 (62) | |
| Advanced degree | 240 (21) | 92 (20) | 332 (21) | |
| Network Site | 0.03 | |||
| California | 326 (29) | 136 (30) | 462 (29) | |
| Michigan | 46 (4) | 23 (5) | 69 (4) | |
| Pennsylvania | 264 (24) | 91 (20) | 355 (23) | |
| Tennessee | 144 (13) | 40 (9) | 184 (12) | |
| Texas | 139 (12) | 56 (12) | 195 (12) | |
| Washington | 104 (9) | 61 (13) | 165 (11) | |
| Wisconsin | 99 (9) | 48 (11) | 147 (9) | |
| Week of Illness Onset | <0.01 | |||
| Oct 10, 2021 – Nov 16, 2021 | 92 (8) | 13 (3) | 105 (7) | |
| Nov 17, 2021 – Dec 4, 2021 | 237 (21) | 32 (7) | 269 (17) | |
| Dec 5, 2021 – Jan 1, 2022 | 206 (18) | 98 (22) | 304 (19) | |
| Jan 2, 2022 – Jan 29, 2022 | 139 (12) | 184 (40) | 323 (21) | |
| Jan 30, 2022 – Feb 26, 2022 | 153 (14) | 59 (13) | 212 (13) | |
| Feb 27, 2022 – Mar 26, 2022 | 240 (21) | 32 (7) | 272 (17) | |
| Mar 27, 2022 – Apr 15, 2022 | 55 (5) | 37 (8) | 92 (6) | |
Data reported as number (column percent) unless noted
P-value from Chi-square test comparing COVID-19 negative with positive
Race and Hispanic ethnicity as participant reported at enrollment. Participants could select more than one. ‘Other’ category includes Native Hawaiian or other Pacific Islander and American Indian or Alaska Native.
Conditions included heart disease, lung disease, diabetes, cancer, liver/kidney disease, immune suppression, or high blood pressure.
High-risk SARS-CoV-2 exposures included healthcare work in close contact with patients, close contact in the 14 days before illness onset with either a person with laboratory-confirmed SARS-CoV-2 or a household member with laboratory-confirmed SARS-CoV-2 or symptoms consistent with COVID-19-like illness.
Unknown for four SARS-CoV-2-negative participants