Table 4.
Genotype and allele frequencies of Keap1rs11085735 in studied groups.
| Polymorphism of Keap1 A> C n (%) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Genotype | All patients | Severe preeclampsia | Mild preeclampsia | Controls | ||||
| AA | 6 (4) | 2 (3.6) | - | 4 (4.2) | - | 3 (2) | ||
| AC | 25 (16.7) | OR | 0.32 * | 8 (14.5) | 0.3 * | 17 (17.9) | 0.32a | 39 (26) |
| (95%CI) | (0.073-1.4) | (0.04-2.2) | (0.066-1.62) | |||||
| P | 0.11 | 0.21 | 0.15 | |||||
| CC | 119 (79.3) | OR | 0.55* | 45 (81.8) | 0.62b | 74 (77.9) | 0.51b | 108 (72) |
| (95%CI) | (0.134-2.25)- | (0.1-3.9) | (0.112-2.4) | |||||
| P | 0.4 | 0.57 | 0.38 | |||||
| A | 37 (12.3) | - | 12 (10.9) | - | 25 (13.2) | - | 45 (15) | |
| C | 263 (87.7) | OR | 1.25 | 98 (89.1) | 1.44 | 165 (86.8) | 1.16 | 255 (85) |
| (95%CI) | (0.78-2) | (0.73-2.8) | (0.68-1.97) | |||||
| P | 0.34 | 0.28 | 0.57 | |||||
Comparisons were made with controls.
*
Compared with AA genotype.