Distribution of CTL and HTL alleles among the candidate proteins. (A) Number and strength of binding epitopes of CTL alleles predicted by NetMHCpan-4.1. (B) Violin plot showing the distribution of CTL allele-binding epitopes based on percentage rank [A1 (HLA-A*01:01), A2 (HLA-A*02:01), A3(HLA-A*03:01), A24 (HLA-A*24:02), and B7 (HLA-B*07:02)]. (C) Number and strength of HTL allele-binding epitopes predicted by NetMHCIIpan-4.0. (D) Violin plot showing the distribution of binding epitopes based on percentage rank for human (HLA-DQ, HLA-DR, HLA-DP) and mouse (H-2-I) HTL alleles. SB and WB represent strong and weak binders, respectively.