TABLE 4.
Cellular and humoral immune responses to B. burgdorferi antigens according to duration of acute infection
| Antigen | Resulta for patients with indicated duration of acute infection prior to sampling (days)
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Proliferation assay
|
IgM ELISA
|
IgG ELISA
|
|||||||
| <7 (n = 31) | ≥7 (n = 8) | P | <7 (n = 31) | ≥7 (n = 8) | P | <7 (n = 31) | ≥7 (n = 8) | P | |
| B. burgdorferi lysate | 13 (42) | 4 (50) | 0.7 | 10 (32) | 4 (50) | 0.4 | 3 (10) | 2 (25) | 0.3 |
| FlaB | 2 (6) | 1 (13) | 0.5 | 8 (26) | 4 (50) | 0.2 | 5 (16) | 5 (63) | 0.02 |
| OspC | 7 (23) | 1 (13) | 1.0 | 12 (39) | 6 (75) | 0.1 | 11 (35) | 4 (50) | 0.7 |
| OspA | 8 (26) | 0 (0) | 0.2 | 2 (6) | 1 (13) | 0.5 | 3 (10) | 0 (0) | 1.0 |
a
Except for P values, results are presented as number (percent) of samples testing positive.