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. 2023 Jan 21;9(2):e13147. doi: 10.1016/j.heliyon.2023.e13147

Table 2.

Top 10 gene ontology (GO) terms in all three GO domains (biological processes, cellular component and molecular function) calculated for CoD24mo group.

GO.ID Term Annotated Significant Expected P-value
Biological processes GO:0051094 positive regulation of developmental processes 627 41 14·86 1·90E-09
GO:0051239 regulation of multicellular organismal processes 1467 68 34·78 1·20E-08
GO:0007154 cell communication 3247 117 76·98 2·30E-08
GO:0009605 response to external stimulus 1093 55 25·91 3·20E-08
GO:0045597 positive regulation of cell differentiation 465 32 11·02 4·50E-08
GO:0051240 positive regulation of multicellular organismal process 791 44 18·75 6·30E-08
GO:0023052 signaling 3233 115 76·65 7·90E-08
GO:0009888 tissue development 860 46 20·39 9·60E-08
GO:0050793 regulation of developmental process 1293 60 30·65 1·20E-07
Cellular component GO:0031225 anchored component of membrane 38 5 0·9 1·85E-03
GO:0000788 nuclear nucleosome 13 3 0·31 3·10E-03
GO:0005886 plasma membrane 2201 69 51·88 5·01E-03
GO:0071944 cell periphery 2248 69 52·98 8·35E-03
GO:0031224 intrinsic component of membrane 2271 69 53·53 1·06E-02
GO:0031226 intrinsic component of plasma membrane 592 23 13·95 1·24E-02
GO:0005887 integral component of plasma membrane 563 22 13·27 1·35E-02
GO:0016021 integral component of membrane 2236 66 52·7 2·34E-02
GO:0044459 plasma membrane part 1100 36 25·93 2·56E-02
GO:0009986 cell surface 335 14 7·9 2·72E-02
Molecular function GO:0001077 transcriptional activator activity, RNA ··· 130 13 3·05 1·10E-05
GO:0019955 cytokine binding 51 8 1·2 2·20E-05
GO:0001228 transcriptional activator activity, RNA ··· 195 15 4·57 5·30E-05
GO:0000981 RNA polymerase II transcription factor a··· 396 23 9·29 5·40E-05
GO:0000982 transcription factor activity, RNA polym··· 202 15 4·74 7·90E-05
GO:0003700 DNA binding transcription factor activit··· 732 34 17·17 8·80E-05
GO:0038023 signaling receptor activity 320 19 7·51 1·80E-04
GO:0046983 protein dimerization activity 717 31 16·82 6·50E-04
GO:0060089 molecular transducer activity 443 22 10·39 7·10E-04
GO:0001159 core promoter proximal region DNA bindin··· 206 13 4·83 1·11E-03