Table 2.
In- and off-laboratory gait and mobility assessment
| Healthy subjects | Cerebellar disorders | F1,153 | p | |
|---|---|---|---|---|
| In-laboratory gait measures | ||||
| Gait velocity [m/s] | 1.2 ± 0.2 | 0.9 ± 0.2* | 39.9 | < 0.001 |
| Stride length [m] | 1.3 ± 0.2 | 1.1 ± 0.3 | 34.5 | < 0.001 |
| Stride time [s] | 1.1 ± 0.1 | 1.3 ± 0.1* | 9.0 | 0.003 |
| Swing phase [%] | 38 ± 2 | 37 ± 2 | 63.4 | < 0.001 |
| Double support phase [%] | 24 ± 4 | 30 ± 9* | 22.6 | < 0.001 |
| Base of support [m] | 0.08 ± 0.03 | 0.15 ± 0.06* | 65.7 | < 0.001 |
| Base of support CV [%] | 24 ± 15 | 24 ± 12 | 0.7 | n.s |
| Stride length CV [%] | 2.2 ± 1.1 | 5.6 ± 4.6* | 21.3 | < 0.001 |
| Stride time CV [%] | 2.3 ± 1.9 | 5.2 ± 1.2* | 28.1 | < 0.001 |
| Gait asymmetry index [%] | 2.5 ± 1.5 | 6.8 ± 3.7* | 24.5 | < 0.001 |
| Phase synchronization [%] | 4.1 ± 1.4 | 9.9 ± 5.3* | 17.3 | < 0.001 |
| Mobility | ||||
| Adherence | ||||
| Days recorded [d] | 12.3 ± 1.9 | 12.4 ± 1.2 | 0.2 | n.s |
| Time sensor worn [%] | 96 ± 12 | 99 ± 6 | 0.8 | n.s |
| Volume | ||||
| Median step count ± SD [#] | 10,208 ± 3,299 | 6305 ± 3,302* | 45.1 | < 0.001 |
| Mean ambulation % ± SD [%] | 8.7 ± 2.6 | 5.7 ± 2.5* | 45.2 | < 0.001 |
| Mean sedentary % ± SD [%] | 27.8 ± 7.7 | 34.5 ± 10.2* | 39.2 | < 0.001 |
| Median sleep % ± SD [%] | 40.8 ± 6.7 | 42.3 ± 9.9 | 0.9 | n.s |
| Activity | ||||
| Median ambulation bout # ± SD [#] | 456 ± 134 | 338 ± 139* | 23.8 | < 0.001 |
| Ambulatory bout duration ± SD [s] | 17 ± 5 | 15 ± 4 | 9.8 | .0.02 |
| Mean daily intensity ± SD [MET] | 35 ± 1 | 33 ± 1* | 48.7 | < 0.001 |
| Pattern | ||||
| Mean ambulation alpha ± SD | 1.42 ± 0.04 | 1.43 ± 0.04 | 1.5 | n.s |
| Median sit-walk transitions ± SD | 40 ± 16 | 36 ± 13 | 2.7 | n.s |
*indicates significant difference in the Sheffé posthoc comparison (to healthy subjects)
CV, coefficient of variation; SD, standard deviation