Table 2.

Correlations between TAM subset numbers and clinicopathological characteristics in Luminal-B breast cancer

Clinicopathological features		CD68	CD163			CSF-1R			CD206
		Total	M2-like	M1-like	Ratio	M2-like	M1-like	Ratio	M2-like	M1-like	Ratio
Age1	r	− 0.207	− 0.237	− 0.032	− 0.134	− 0.281	0.128	− 0.242	− 0.009	− 0.115	0.071
	P	0.065	0.034	0.777	0.237	0.011	0.259	0.031	0.935	0.311	0.534
Menopausal status2	P	0.228	0.475	0.084	0.186	0.409	0.441	0.462	0.630	0.654	0.425
Premenopausal	Median	129.33	153	1	106	57.33	61.67	0.70	49.67	78.33	0.81
Perimenopausal	Median	62.67	191.67	1	191.67	28	32	1.83	75.67	15.5	3.26
Postmenopausal	Median	102.17	131.42	1	64	33.42	54.33	0.75	67.83	52.67	1.25
Tumour grade2	P	< 0.001*	< 0.001*	0.644	0.048	< 0.001*	0.439	0.001*	0.175	0.071	0.663
Grade 1	Median	50.17	102.33	1	102.33	27.5	22.67	4.88	37.5	12.67	5.56
Grade 2	Median	85	95.67	1	57	19	46.67	0.34	58	37.33	1.77
Grade 3	Median	136.33	216	1	191.67	102	39.5	1.87	75.67	83.67	0.80
Tumour size1	r	− 0.007	0.083	− 0.071	0.102	0.109	− 0.153	0.175	− 0.045	0.008	0.006
	P	0.948	0.462	0.532	0.367	0.334	0.177	0.121	0.693	0.944	0.955
Lymph node status3	P	0.650	0.760	0.712	0.813	0.661	0.472	0.953	0.622	0.788	0.937
Positive	Median	116.33	155	1	130.67	53.67	63.33	0.75	75.33	61.67	1.07
Negative	Median	109.33	132.5	1	104.83	34.44	38.17	0.75	57.5	46.67	0.88
Lymphovascular invasion3	P	0.981	0.880	0.641	0.664	0.683	0.674	0.739	0.709	0.775	0.647
Positive	Median	125.33	174.00	1	174.00	30.33	63.83	1.29	77.83	39.83	2.21
Negative	Median	110.58	132.5	1	101.5	42.33	40.42	0.75	58.33	52.17	0.87

*P ≤ 0.005

¹Spearman’s rho

²Kruskal–Wallis test

³Mann–Whitney U test

r—correlation coefficient, P—P value, Median—median TAM subset number