Table 3.

Correlations between TAM subset numbers and clinicopathological characteristics in Luminal-A breast cancer

Clinicopathological features		CD68	CD163			CSF-1R			CD206
		Total	M2-like	M1-like	Ratio	M2-like	M1-like	Ratio	M2-like	M1-like	Ratio
Agea	r	− 0.176	− 0.153	0.006	− 0.105	− 0.134	− 0.096	− 0.015	0.074	− 0.128	0.139
	P	0.031	0.061	0.944	0.200	0.101	0.245	0.859	0.371	0.119	0.090
Menopausal statusb	P	0.440	0.977	0.996	0.969	0.735	0.311	0.232	0.450	0.416	0.263
Premenopausal	Median	46.33	98.67	1	82	9.33	17.33	0.41	79.67	1	52
Perimenopausal	Median	56.5	94.7	1	97.4	8	34.92	0.19	65.83	1	43
Postmenopausal	Median	41	80	1	71.33	9.33	24.33	0.31	87.67	1	69.67
Tumour gradeb	P	0.034	0.025	0.474	0.111	0.008	0.674	0.284	0.791	0.524	0.837
Grade 1	Median	32.5	70.83	1	67.5	6.67	16.17	0.35	87.67	1	66.17
Grade 2	Median	42.17	93.37	1 1	67.83	8	25.17	0.29	82.83	1	69
Grade 3	Median	66.5	150.75		150.75	22.67	30.33	0.43	90.17	1	76.17
Tumour sizea	r	0.205	0.158	0.005	0.142	0.110	0.165	0.012	− 0.154	0.224	− 0.220
	P	0.012	0.054	0.953	0.083	0.180	0.044	0.887	0.060	0.006	0.007
Lymph node statusc	P	0.353	0.291	0.958	0.336	0.510	0.229	0.797	0.578	0.718	0.561
Positive	Median	45.67	98.67	1	84.67	9.67	28.33	0.35	83.67	1	69.67
Negative	Median	39.17	81	1	65.33	7.5	17.83	0.31	93.67	1	69.5
Lymphovascular invasionc	P	0.975	0.117	0.214	0.075	0.417	0.749	0.367	0.094	0.266	0.109
Positive	Median	40.5	112.42	1	112.42	4	20.33	0.14	129.92	1	129.92
Negative	Median	41	76.67	1	68	8.33	21	0.35	82.67	1	69.33

*P  ≤  0.005

^aSpearman’s rho

^bKruskal–Wallis test

^cMann–Whitney U test

r—correlation coefficient, P—P value, Median—median TAM subset number