Table 5.
Clinicopathological features | CD68 | CD163 | CSF-1R | CD206 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Total | M2-like | M1-like | Ratio | M2-like | M1-like | Ratio | M2-like | M1-like | Ratio | ||
Agea | R | 0.097 | 0.001 | 0.052 | 0.005 | 0.121 | − 0.168 | 0.136 | 0.065 | 0.040 | − 0.011 |
P | 0.374 | 0.989 | 0.633 | 0.967 | 0.267 | 0.123 | 0.212 | 0.555 | 0.712 | 0.919 | |
Menopausal statusb | P | 0.734 | 0.075 | 0.040 | 0.015 | 0.730 | 0.249 | 0.505 | 0.622 | 0.821 | 0.856 |
Premenopausal | Median | 35.5 | 175.83 | 1 | 131.33 | 49.17 | 1 | 19.17 | 48.5 | 1 | 18.3 |
Perimenopausal | Median | 15.33 | 44 | 1 | 39.67 | 62.33 | 1 | 55 | 19.33 | 5.33 | 1.88 |
Postmenopausal | Median | 37.33 | 142 | 1 | 142 | 82.67 | 1 | 82.67 | 61 | 1 | 20.67 |
Tumour gradeb | P | 0.055 | 0.034 | 0.181 | 0.037 | 0. 971 | 0.547 | 0. 859 | 0.446 | 0.270 | 0.929 |
Grade 1 | Median | 2.33 | 16.5 | 1 | 16.50 | 203.00 | 1 | 203.00 | 35.00 | 1 | 35.00 |
Grade 2 | Median | 14.67 | 61 | 1 | 46.33 | 63.00 | 1 | 36.00 | 36.67 | 1 | 25.00 |
Grade 3 | Median | 39.92 | 146.83 | 1 | 128.50 | 79.5 | 1 | 53.17 | 50.00 | 1 | 16.26 |
Tumour sizea | r | − 0.008 | 1460.040 | 0.078 | 0.078 | 0.127 | − 0.113 | 0.148 | 0.057 | − 0.002 | 0.095 |
P | 0.946 | 0.719 | 0.479 | 0.480 | 0.248 | 0.305 | 0.262 | 0.605 | 0.986 | 0.388 | |
Lymph node statusb | P | 0.877 | 0.779 | 0.349 | 0.493 | 0.727 | 0.625 | 0.810 | 0.412 | 0.931 | 0.666 |
Positive | Median | 36 | 142 | 1 | 115 | 51.33 | 1 | 35.67 | 40.67 | 1 | 20.67 |
Negative | Median | 35 | 112.67 | 1 | 89 | 97.33 | 1 | 62.33 | 48.33 | 1 | 17 |
Lymphovascular invasionb | P | 0.141 | 0.028 | 0.208 | 0.023 | 0.767 | 0.021 | 0.109 | 0.981 | 0.083 | 0.136 |
Positive | Median | 92.67 | 184 | 1 | 182 | 43.67 | 18.67 | 1.27 | 45.33 | 28.33 | 0.98 |
Negative | Median | 24.33 | 94.17 | 1 | 81.67 | 75.83 | 1 | 58.67 | 45.5 | 1 | 20.67 |
*P ≤ 0.005
aSpearman’s rho
bKruskal–Wallis test
cMann–Whitney U test
r—correlation coefficient, P—P value, Median—median TAM subset number