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. 2022 May 17;45(5):477–491. doi: 10.1007/s40264-022-01176-1

Table 3.

Top four topics discovered by LDA by prevalence

Topic focus Keywords Prevalence (%)
Deep learning Embed, LSTM, layer, model 7.01
Adverse events post-vaccination Vaccine, VAERS, Guillain–Barré syndrome, report 6.17
Signal detection BCPNN, PRR, Gamma Poisson Shrinker, shrinkage, method 5.87
Information extraction/NLP Annotate, entity, ADE, sentence 5.70

Topic focus is a subjective assessment of the content based on the most relevant keywords for each topic, as determined by setting the relevancy metric λ to 0.3 in the ‘LDAvis’ package (see electronic supplementary Table S1 for a full list of topics). NLP natural language processing, VAERS Vaccine Adverse Event Reporting System, BCPNN Bayesian Confidence Propagation Neural Network