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. 2022 Jul 3;12(2):1137–1156. doi: 10.1002/cam4.4968

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© 2022 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Kaplan–Meier curves according to mutational subgroups (i.e., all‐wild‐type + pMMR, KRAS _mut + pMMR, KRAS _mut + PIK3CA _mut + pMMR, PIK3CA _mut + pMMR, BRAF _mut + pMMR, BRAF _mut + dMMR, other+pMMR, and other+dMMR) in colorectal cancer patients within the Netherlands Cohort Study (NLCS, 1986–2006), showing (A) CRC‐specific survival (median survival times: KRAS _mut + pMMR, 7.16 years and BRAF _mut + pMMR, 2.48 years) and (B) overall survival (median survival times: All‐wild‐type + pMMR, 5.73 years; KRAS _mut + pMMR, 3.49 years; KRAS _mut + PIK3CA _mut + pMMR, 4.79 years; PIK3CA _mut + pMMR, 5.91 years; BRAF _mut + pMMR, 1.83 years; BRAF _mut + dMMR, 5.46 years; other + pMMR, 4.25 years; other + dMMR, 8.04 years).