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. 2023 Jan 27;9:11. doi: 10.1038/s41531-023-00462-8

Table 3.

The risk of Parkinson’s disease according to the diabetes severity score.

Total Events (n) Incidence rate (per 1000 person-years) Model 1 Model 2
Total population
0 1,221,120 5378 0.640 1 (ref.) 1 (ref.)
1 583,678 4667 1.153 1.22 (1.17, 1.27) 1.09 (1.04, 1.15)
2 332,552 3485 1.527 1.48 (1.41, 1.54) 1.28 (1.22, 1.35)
3 153,646 2141 2.076 1.84 (1.75, 1.93) 1.55 (1.46, 1.65)
4 55,942 1052 2.927 2.43 (2.28, 2.60) 1.96 (1.82, 2.11)
5 13,663 282 3.385 2.69 (2.39, 3.04) 2.08 (1.83, 2.36)
6 1471 41 4.846 3.67 (2.70, 4.99) 2.78 (2.05, 3.79)
Men
0 769,185 2833 0.538 1 (ref.) 1 (ref.)
1 328,400 2236 0.990 1.22 (1.15, 1.29) 1.09 (1.01, 1.17)
2 176,952 1581 1.320 1.44 (1.35, 1.53) 1.24 (1.15, 1.35)
3 75,135 905 1.837 1.77 (1.64, 1.91) 1.48 (1.36, 1.63)
4 25,592 426 2.682 2.35 (2.12, 2.61) 1.89 (1.69, 2.12)
5 5964 105 3.047 2.57 (2.11, 3.12) 1.98 (1.61, 2.42)
6 598 13 3.986 3.24 (1.88, 5.58) 2.44 (1.41, 4.22)
Women
0 451,935 2545 0.81148 1 (ref.) 1 (ref.)
1 255,278 2431 1.35926 1.22 (1.15, 1.29) 1.10 (1.02, 1.19)
2 155,600 1904 1.75594 1.50 (1.41, 1.59) 1.32 (1.23, 1.42)
3 78,511 1236 2.29444 1.88 (1.75, 2.01) 1.62 (1.49, 1.75)
4 30,350 626 3.12195 2.47 (2.26, 2.70) 2.02 (1.83, 2.23)
5 7699 177 3.62248 2.76 (2.37, 3.22) 2.17 (1.85, 2.54)
6 873 28 5.3852 3.93 (2.71, 5.71) 3.02 (2.08, 4.40)

Model 1: adjusted for age and sex.

Model 2: adjusted for age, sex, BMI, alcohol drinking, smoking, regular exercise, hypertension, dyslipidemia, and depression.