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. 2022 Jul 21;12(2):1972–1983. doi: 10.1002/cam4.5034

FIGURE 1.

FIGURE 1

The strategies and analyzing methods of this study are shown. (A) The strategy, participants, targeted genes, and analyzing approaches are shown. (B) Relationships among 152 cancer predisposition genes, 299 cancer driver genes, and 568 cancer driver genes are shown. (C) WGS analysis methods. We analyzed variants of coding and non‐coding areas in protein‐coding genes, and non‐coding genes and regulatory areas using the ClinVar database, and prediction tools (e.g., CADD, RegulomeDB, and Funseq2) to analyze null variants. WGS, whole‐genome sequencing.