Table 4.

Drugs with the highest number of interactions from each drug category with the common dental drugs

Disease	Drug	Amox	Pen	Met	Pril	Epi	Ibu	Lid	Ace	Flu	Acy	Dia
Antihypertensive	losartan						mo			mo		mo
Antiglycemic	Glibenclamide					mo	mo			ma
Antihyperlipidemic	Rosuvastatin Atorvastatin			mo						mi		mi
				mo						ma		ma
Heart Disease Drugs	Warfarin	mo		ma	mo		ma		mi	ma
(DMARDs)	Methotrexate	ma	ma				ma		mo	mo	mo
Gastrointestinal Disease Drugs	Famotidine Omepraole			mi			mi	mi	mi	mo	mo	mo
										mo
Neurological and Depression	Sertraline			mi			mo		mo	mo	mo	mi
Osteoporosis	Alendronate						mo
Analgesia	Celecoxib Diclofenac			mo			mo			mo	mo
							mo			mo
+Hypothyroidism	Levothyroxine					mo
High Uric Acid	Allopurinol	mi
Prostate	Tamsulosin									mo	mo	mo
Kidney failure	Furosemide						mo					mo
Asthma	Fluticasone/Salmetrol	mi	mi	mi	mi	mi	mo	mi	mi	mi	mo	mi	mo
	Symbicort spray	mi	mi	mi	mi	mo	mo	mi	mi	mo	mi	mi
Alzheimer	Yasnal			mo			mi			mi	mi
Multiple Sclerosis	Tizanidine			mi						mo	ma	mo
Sleep Disorders	Chlordiazpoxide				mo			mo			mo	mo
	Alprazolam				mo			mo		ma	ma
Epilepsy	Carbamazepine			mo				mi	mo	mo	mo	mo
Liver Cyst	Albendazole							mi
Parkinson	Levodopa			mo		mo						mo

DMARDs =Disease-modifying antirheumatic drugs, mo=moderate, ma=major, mi=minor

Amox=Amoxicillin, Pen=Penicillin, Met= Metronidazole, Pril= Prilocaine, Epi=Epinephrine

Ibu= Ibuprofen, Lid= Lidocaine, Ace= Acetaminophen, Flu+ Fluconazole, Acy=Acyclovir, Dia=Diazepam