Table 1.
Baseline characteristics of patients
| Variables |
Total N = 222 |
IVH (Grade I-II) N = 137 |
NO-IVH N = 85 |
p |
|---|---|---|---|---|
| Gender | 0.564 | |||
| Male | 116 (52.3%) | 69 (50.4%) | 47 (55.3%) | |
| Female | 106 (47.7%) | 68 (49.6%) | 38 (44.7%) | |
| GA(weeks) | 0.015 | |||
| < 30 | 62 (27.9%) | 48 (35.0%) | 14 (16.5%) | |
| 30–34 + 6 | 94 (42.3%) | 55 (40.1%) | 39 (45.9%) | |
| 35–36 + 6 | 38 (17.1%) | 18 (13.1%) | 20 (23.5%) | |
| ≥ 37 | 28 (12.6%) | 16 (11.7%) | 12 (14.1%) | |
| BW (kilograms) | 0.258 | |||
| < 1500 | 108 (48.6%) | 72 (52.6%) | 36 (42.4%) | |
| 1500–2500 | 83 (37.4%) | 49 (35.8%) | 34 (40.0%) | |
| ≥ 2500 | 31 (14.0%) | 16 (11.7%) | 15 (17.6%) | |
| Length | 41.7 ± 5.31 | 41.0 ± 5.64 | 42.8 ± 4.52 | 0.009 |
| HC | 29.3 ± 2.69 | 28.9 ± 2.69 | 29.9 ± 2.59 | 0.010 |
| UC | 0.054 | |||
| No | 129 (58.1%) | 87 (63.5%) | 42 (49.4%) | |
| Yes | 93 (41.9%) | 50 (36.5%) | 43 (50.6%) | |
| PROM | <0.001 | |||
| No | 144 (64.9%) | 109 (79.6%) | 35 (41.2%) | |
| Yes | 78 (35.1%) | 28 (20.4%) | 50 (58.8%) | |
| Multiple births | 0.005 | |||
| No | 156 (70.3%) | 106 (77.4%) | 50 (58.8%) | |
| Yes | 66 (29.7%) | 31 (22.6%) | 35 (41.2%) | |
| Apgar score | 0.525 | |||
| ＞7 | 135 (60.8%) | 85 (62.0%) | 50 (58.8%) | |
| 4–7 | 76 (34.2%) | 47 (34.3%) | 29 (34.1%) | |
| ≤ 3 | 11 (4.95%) | 5 (3.65%) | 6 (7.06%) | |
| PS dosage | 0.002 | |||
| ＞100 | 189 (85.1%) | 125 (91.2%) | 64 (75.3%) | |
| ≤ 100 | 33 (14.9%) | 12 (8.76%) | 21 (24.7%) | |
| PS | 0.654 | |||
| No | 172 (77.5%) | 108 (78.8%) | 64 (75.3%) | |
| Yes | 50 (22.5%) | 29 (21.2%) | 21 (24.7%) | |
| PH1 | 7.31 ± 0.08 | 7.34 ± 0.06 | 7.26 ± 0.07 | <0.001 |
| PaO21 | 76.6 ± 23.9 | 82.8 ± 23.5 | 66.7 ± 21.1 | <0.001 |
| PaCO21 | 38.6 ± 9.56 | 35.4 ± 8.14 | 43.7 ± 9.49 | <0.001 |
| BE1 | -7.16 ± 2.96 | -6.94 ± 2.98 | -7.52 ± 2.91 | 0.157 |
| PH2 | 7.35 ± 0.10 | 7.36 ± 0.10 | 7.35 ± 0.09 | 0.469 |
| PaO22 | 83.7 ± 21.6 | 85.0 ± 20.7 | 81.6 ± 23.0 | 0.268 |
| PaCO22 | 36.9 ± 37.8 | 33.5 ± 11.0 | 42.3 ± 59.3 | 0.181 |
| BE2 | -7.02 ± 3.30 | -6.67 ± 3.21 | -7.57 ± 3.37 | 0.050 |
| Invasive ventilation | 0.167 | |||
| No | 111 (50.0%) | 63 (46.0%) | 48 (56.5%) | |
| Yes | 111 (50.0%) | 74 (54.0%) | 37 (43.5%) |
GA gestational age, BW Birth weight, HC Uterine contraction, HC Head circumference, PROM premature rupture of membrane, PS pulmonary surfactant, PH1, PaO21, PaCO21 and BE1 represent the first blood gas analysis value, PH2, PaO22, PaCO22 and BE2 represent the second blood gas analysis value