Table 1. List of genetic instruments for periodontitis selected by TwoSampleMR.
| SNP | CHR | POS | Effect allele | REF allele | MAF | Overlapped gene | Beta for exposure | SE for exposure | P-value for exposure |
|---|---|---|---|---|---|---|---|---|---|
| rs1633266 | 1 | 159005977 | T | C | 0.32 | IFI16 | −0.93 | 0.17 | 3.09 × 10−8 |
| rs17718700 | 3 | 29055145 | C | T | 0.04 | – | 1.22 | 0.22 | 4.58 × 10−8 |
| rs17184007 | 12 | 67594578 | C | T | 0.05 | – | 1.35 | 0.23 | 6.86 × 10−9 |
| rs9557237 | 13 | 100110910 | C | G | 0.18 | – | 1.33 | 0.24 | 1.42 × 10−8 |
| rs3811273 | 14 | 22715158 | G | A | 0.16 | – | 1.22 | 0.2 | 2.06 × 10−9 |
| rs1156327 | 16 | 19348524 | C | T | 0.21 | – | −1.45 | 0.23 | 3.01 × 10−10 |
Notes.
- SNP
- the label of single-nucleotide polymorphism
- MR
- Mendelian randomization
- CHR
- chromosome
- POS
- position
- REF allele
- reference allele
- MAF
- Minor Allele Frequency
- SE
- Standard Error
- IFI16
- Interferon Gamma Inducible Protein 16