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. 2023 Jan 28;13:1616. doi: 10.1038/s41598-023-28737-3

Table 6.

Assay results for the determination of four studied drugs in their co-formulated prepared tablet by the suggested HPLC technique.

Ratio Suggested technique Comparison method23
Concentration taken (µg/mL) Concentration found (µg/mL) % Found % Found
PAR LVC PHN AMB PAR LVC PHN AMB PAR LVC PHN AMB PAR LVC PHN AMB
65:1:1:6 325.0 5.0 5.0 30.0 320.886 5.064 4.953 30.457 98.73 101.28 99.06 101.52 101.93 98.90 101.92 98.58
390.0 6.0 6.0 36.0 397.759 5.901 6.051 35.208 101.99 98.35 100.85 97.8 99.54 101.21 98.43 101.50
455.0 7.0 7.0 42.0 451.271 7.043 6.981 42.361 99.18 100.61 99.73 100.86 100.12 99.58 100.49 99.49
Mean 99.97 100.08 99.88 100.06 100.53 99.19 100.28 99.85
 ± S.D 1.77 1.54 0.91 1.99 1.25 1.19 1.754 1.49
t-test 0.45 0.16 0.35 0.075 The tabulated t and F values are 2.78 and 19.00, respectively at P = 0.0542
F-test 2.01 1.68 3.76 1.76