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. 2023 Jan 10;66(2):1157–1171. doi: 10.1021/acs.jmedchem.2c01521

Table 2. 2-Methyl-pyrimidine Core SARa.

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a

Each Ki value reported is an average of at least two measurements with a 10-point dose–response curve. Rat CLu was calculated by dividing measured rat clearance by rat plasma free fraction.