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. 2023 Jan 6;66(2):1221–1238. doi: 10.1021/acs.jmedchem.2c00775

Table 3. Inhibitory Activities against T. cruzi: Probing the 4-Position with Cyclic Amines.

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a

T. cruzi high-content infected cell assay, IC50 of total parasite count; SI = IC50/CC50 against background U2OS cell line.

b

Chiral enantiomer.