Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
TRPA1 antagonist binding sites. Side view of hTRPA1 using a cryoEM structure (PDB: 6V9Y). Unresolved Ankyrin repeats 1–11 are shown as boxes. The mutated residues are shown in red when resolved and indicated by arrows. The different sites with the respective mutations are labeled as binding site 1a (F909T and T874V) with bound A-967079 (compound 4) in blue, binding site 1b (M911A), binding site 2 (N855S), and binding site 3 (G238K/N249S/K270N).
