Table 7. Kinetic and Thermodynamic Solubility Data of Representative Compounds with Antibacterial Activity.

					free fraction [%]
Cpd.	log D Calc.	log P Calc.	kinetic solub. [μM]	thermodyn. solub. [μM]	human	mouse
1	2.1	5.8	12	6.6	<0.1	<0.1
27	2.59	5.94	>80	92.4	0.016	0.01
36	2.26	2.74	35	3	<0.1	0.3
51	1.52	4.87	41	18	0.13	0.3
59	1.66	2.14	20	70	<0.1	0.5
65	2.56	2.74	30	25	<0.1	<0.1
71	1.12	2.21	59	2760	0.11	0.2