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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Acta Trop. 2022 Nov 19;238:106752. doi: 10.1016/j.actatropica.2022.106752

Table 3.

Schistosome Infection Status at 6-month Follow-up as Compared to Baseline Infection (n=28).

Cleared
infection
Infected but
had >7-fold
decrease in
CAA
Infected and
did not have
at least 7-fold
decrease in
CAA
Uninfected at
baseline and
stayed
uninfected
Uninfected at
baseline and
became
infected at
month 6
No. of individuals 7 7 5 6 3
Female 7 (100%) 5 (71.4%) 2 (40%) 2 (33.3%) 3 (100%)
Median [IQR] CAA fold change from baseline to month 6 −641 [−23.7 to −5190] −85.3 [−29.6 to −296.1] −3.2 [−2.9 to −6.8] n/a +62 [+58 to +80]
Median [IQR] difference in eggs per gram of stool between baseline and month 6 −52.8 [−24 to −81.6]

*All eggs cleared at 6 months
−21.6 [−4.8 to −72]

*All but 2 cleared eggs at 6 months
−33.6 [−9.6 to −52.8]

*All eggs cleared at 6 months
n/a 0*
Median [IQR] 6-month Mayo score 2 [0-2] 2 [2-4] 2 [2-3] 2 [0-2] 2 [0-2]
Median [IQR] difference in Mayo score between baseline and month 6 − 2 [−1 to −3] 0 [+2 to −0] −0.5 [+1 to −1.5] 0 [0 to −2] 0 [0 to +2]
*

All newly infected people were diagnosed by CAA only.

Representative pre-post gastrointestinal mucosal findings in three individuals are shown in Figure 3. These individuals demonstrated examples of mucosal changes that occurred in those with improvement, worsening, or no change in the severity of mucosal abnormalities.