Table 4.

Changes in Baseline Clinical Measurements After 6 Months of Follow-up in Individuals Who Were Effectively Treated for S. mansoni Infection.

Characteristic	Baseline (Month 0) (n=14)	Follow-up (Month 6) (n=14)
	Number (%) or Median [IQR]	Number (%) or Median [IQR]
White blood cell count (103/uL)*	4.7 [3.6-5.5]	3.6 [3.2-4.7]
Eosinophils (%)*	5.7 [3.1-10.3]	3.5 [1.7-6.3]
Absolute eosinophil count (103/uL)*	0.3 [0.1-0.6]	0.1 [0.1-0.3]
Hemoglobin (g/dL)	13.7 [13.1-14.1]	13.1 [12.6-14.1]
Platelets (cells/μL)	179 [142-230]	180.5 [139-213]
Creatinine (μmol/L)**	55.3 [49.3-71.5]	51 [44.5-61]
AST (U/L)	30.1 [23.8-33.7]	28.6 [25.5-31.7]
ALT (U/L)*	30.7 [29.4-44.1]	26.9 [20-33.3]
ESR (mm/hr)**	32.5 [20-40]	12.5 [10-30]
Systolic blood pressure (mmHg)	110.7 [102.3-118]	111.8 [98.3-122.7]
Diastolic blood pressure (mmHg)	76.7 [71.7-78]	72.7 [71.3-82]
Overall endoscopy findings
Normal (0)	0	2 (14.3%)
Semi-normal (0.5)	0	1 (7.1%)
Mild disease (1)	12 (85.7%)	10 (71.4%)
Moderate disease (2)	2 (14.3%)	1 (7.1%)
Physician’s Overall Rating of Disease Severity
Normal (0)	0	2 (14.3%)
Mild (1)	12 (85.7%)	11 (78.6%)
Moderate (2)	2 (14.3%)	1 (7.1%)
Severe (3)	0	0
Mayo Score (0-12 score)	2 [2-4]	2 [2-2]
Sigmoid colon mucosal features
Mild disease
Patchy or mild erythema	2 (14.3%)	0
Altered vascular pattern	9 (64.3%)	2 (14.3%)
Mild friability	2 (14.3%)	0
Moderate disease
Marked erythema	0	0
Absent vascular markings	0	0
Moderate friability	1 (7.1%)	0
Erosions	0	0
Overall sigmoid mucosal findings**	1 [0-1]	0 [0-0]
(0=Normal, 1=Mild, 2=Moderate, 3=Severe)
Rectum mucosal features
Mild
Patchy or mild erythema	9 (64.3%)	6 (42.9%)
Altered vascular pattern	13 (92.9%)	11 (78.6%)
Mild friability	3 (21.4%)	3 (21.4%)
Moderate
Marked erythema	0	1 (7.1%)
Absent vascular markings	1 (7.1%)	1 (7.1%)
Moderate friability	2 (14.3%)	1 (7.1%)
Erosions	0	0
Overall rectal mucosal findings	1 [1-1]	1 [1-1]
(0=Normal, 1=Mild, 2=Moderate, 3=Severe)

^*p-value < 0.05

^**p-value < 0.01

^***p-value < 0.001