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. Author manuscript; available in PMC: 2023 Jan 28.
Published in final edited form as: Nature. 2022 Apr 6;604(7905):371–376. doi: 10.1038/s41586-022-04555-x

Extended Data Fig. 10 |. A putative common shuttling mechanism between CmWaaL, RodA, ArnT and PglB.

Extended Data Fig. 10 |

a, Structural comparison between CmWaaL and TtRodA (PDB ID 6PL5), coloured on a blue to red rainbow from N to C terminus. The two additional helices (TM1 and TM2) of CmWaaL are in grey. b, A comparison of the putative access pathway for polyprenyl-linked-phosphate containing ligands for CmWaaL, TtRodA, CmArnT (PDB ID 5F15) and ClPglB (PDB ID 5OGL). The equivalent TM helix is shown in red and periplasmic helix in blue. Conserved residues, that may be involved in the shuttling and/or coordination of polyprenyl-phosphate-containing ligands in CmWaaL, TtRodA, CmArnT and ClPglB are shown in sticks and highlighted in blue.