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. 2023 Jan 28;22(1):e12505. doi: 10.1002/rmb2.12505

FIGURE 3.

FIGURE 3

Oocyte proteolytic systems in early embryogenesis. Relative activities of proteolytic systems at each developmental stage are indicated. These stages are mainly studied in mice. Inhibition outcomes are results from gene deletion, gene suppression, or inhibitor assays. Endocytic activity after the 4‐cell stage was not assayed (partly shown with dotted line). Inhibition results using Pitstop2 are indicated. UPS, ubiquitin‐proteasome system