Fig. 3.

Effect of Wee1 inhibition on proliferation, cell survival and cell cycle of EGFRvIII− /+ cells. A Cell cycle distribution was assessed 24 h after adavosertib treatment B Effect of increasing adavosertib concentrations on cell proliferation. Treatment with adavosertib was performed for 72 h. C Cell survival as measured by colony formation after 400 nm adavosertib treatment. Cells were treated for 24 h with adavosertib (n = 4; mean with S.E.M; p-values are obtained by using two-tailed Student´s t-test, *p < 0.05)