TABLE 3.
Symptoms and GMA before and after the nutrient bar test meal in patients with gastroparesis and functional dyspepsia
| Gastroparesis (n = 283) | Functional dyspepsia (n = 112) | p‐value c | |
|---|---|---|---|
| Mean (SD) | Mean (SD) | ||
| Nutrient meal test | |||
| Water taken with smart bar—ml | 53 (45) | 60 (60) | 0.27 e |
| Smart bar—% consumed | 83 (25) | 90 (20) | 0.006 e |
| Test length—min | 8.5 (2.4) | 8.5 (2.2) | 0.38 |
| Symptoms (VAS 0–100) | |||
| Fullness | |||
| Baseline | 28 (30) | 30 (32) | 0.74 |
| Change a | 30 (31) | 33 (30) | 0.33 |
| Hunger | |||
| Baseline | 34 (30) | 33 (31) | 0.93 |
| Change a | −18 (27) d | −20 (26) d | 0.56 |
| Nausea | |||
| Baseline | 29 (31) | 28 (31) | 0.78 |
| Change a | 2 (19) | 6 (22) | 0.55 |
| Bloating | |||
| Baseline | 29 (31) | 28 (31) | 0.67 |
| Change a | 9 (20) | 9 (21) | 0.66 |
| Abdominal discomfort | |||
| Baseline | 26 (30) | 26 (30) | 0.88 |
| Change a | 4 (19) | 5 (17) | 0.11 |
| GMA (distribution of average—%) | |||
| Bradygastria (1–2.4 cpm) | |||
| Baseline | 51 (20) | 50 (20) | 0.66 |
| Change b | −4 (18) | −3 (18) | 0.50 |
| Normogastria (2.5–3.7 cpm) | |||
| Baseline | 19 (13) | 21 (14) | 0.29 |
| Change b | 4 (13) | 4 (15) | 0.92 |
| Tachygastria (3.8–10 cpm) | |||
| Baseline | 23 (12) | 22 (11) | 0.53 |
| Change b | 2 (11) | 0 (10) | 0.22 |
| Duodenal (>10–15 cpm) | |||
| Baseline | 7 (8) | 7 (8) | 0.98 |
| Change b | −1 (7) | −1 (7) | 0.12 |
Abbreviations: GMA, gastric myoelectrical activity; GP, gastroparesis.
a
Mean of 6 values taken at 0, 15, 30, 45, 60, and 90 min after start of test—baseline.
b
Mean of 5 values taken at 15, 30, 45, 60, and 90 min after start of test—baseline.
c
p‐value derived from robust regression of outcome on GP type for baseline and robust regression of change in outcome on GP type and baseline value of outcome.
d
p‐value based on Kruskal–Wallis test due to non‐convergence using robust regression.
e
p‐value based on the t test.
e
Bold values indicates the significant of 0.006 value.