Table 2.
Evaluation of the performance of MRAs and CTA in detecting stenosis of >50% and stenosis of >75% using DSA as the reference standard.
| PETRA-MRA (+) | PETRA-MRA (–) | TOF-MRA (+) | TOF-MRA (–) | CTA (+) | CTA (–) | |
|---|---|---|---|---|---|---|
| Detection of >50% stenosis | ||||||
| DSA (+) | 51 | 1 | 51 | 1 | 50 | 2 |
| DSA (–) | 2 | 36 | 21 | 17 | 14 | 24 |
| Sensitivity (%) | 98.1 (89.7–100.0)a | 98.1 (89.7–100.0)a | 96.2 (86.8–99.5)a | |||
| Specificity (%) | 94.7 (82.3–99.4)a | 44.7 (2861.6–0.7)a | 63.2 (46.0–78.2)a | |||
| PPV (%) | 96.2 (87.0–99.5)a | 70.8 (58.9–81.0)a | 78.1 (66.0–87.5)a | |||
| NPV (%) | 97.2 (85.8–99.9)a | 94.4 (72.7–99.9)a | 92.3 (74.9.7–99.1)a | |||
| Detection of >75% stenosis | ||||||
| DSA (+) | 12 | 2 | 10 | 4 | 14 | 0 |
| DSA (–) | 1 | 75 | 16 | 60 | 11 | 65 |
| Sensitivity (%) | 85.7 (57.2–98.2)a | 71.4 (41.9–91.6)a | 100.0 (76.8–100.0)a | |||
| Specificity (%) | 98.7 (92.9–100.0)a | 78.9 (68.1–87.5)a | 85.5 (75.6–92.5)a | |||
| PPV (%) | 92.3 (64.0–99.8)a | 38.5 (20.2–59.4)a | 56.0 (34.9–75.6)a | |||
| NPV (%) | 97.4 (90.9–99.7)a | 93.8 (84.8–98.3)a | 100.0 (94.5–100.0)a | |||
a
95% confidence interval. CTA, computed tomography angiography; DSA, digital subtraction angiography; MRA, magnetic resonance angiography; NPV, negative predictive value; PETRA, pointwise encoding time reduction; PPV, positive predictive value; TOF, time of flight.