Table 2.
Comparison of plasma aldosterone concentration by tertile of polysomnography sleep parameters in men participants with hypertension under no interfering agents with Bonferroni correction for between group comparison.
| Parameters | T1 | T2 | T3 | p | p1 | p2 | p3 | p for trend |
|---|---|---|---|---|---|---|---|---|
| Log PAC (mean ± SD) | ||||||||
| AHI tertile | 1.11 ± 0.22 | 1.13 ± 0.23 | 1.14 ± 0.23 | 0.125 | 0.682 | 0.128 | 1.00 | 0043 |
| AI tertile | 1.11 ± 0.22 | 1.12 ± 0.23 | 1.15 ± 0.22 | 0.035 | 0.875 | 0.030 | 0.383 | 0.010 |
| HI tertile | 1.12 ± 0.22 | 1.13 ± 0.23 | 1.12 ± 0.23 | 0.425 | 0.581 | 1.00 | 1.00 | 0.601 |
| LSaO2 tertile | 1.10 ± 0.23 | 1.13 ± 0.23 | 1.14 ± 0.22 | 0.044 | 0.519 | 0.039 | 0.849 | 0.013 |
| MSaO2 tertile | 1.12 ± 0.22 | 1.13 ± 0.22 | 1.13 ± 0.23 | 0.670 | 1.000 | 1.000 | 1.000 | 0.384 |
| T90% tertile | 1.13 ± 0.22 | 1.12 ± 0.23 | 1.13 ± 0.23 | 0.509 | 1.000 | 1.000 | 1.000 | 0.831 |
| ODI3 tertile | 1.13 ± 0.22 | 1.12 ± 0.23 | 1.13 ± 0.23 | 0.658 | 0.754 | 0.622 | 0.970 | 0.819 |
| ODI4 tertile | 1.13 ± 0.22 | 1.11 ± 0.24 | 1.13 ± 0.22 | 0.401 | 0.947 | 0.642 | 0.481 | 0.825 |
| Max hypo duration tertile | 1.12 ± 0.23 | 1.12 ± 0.23 | 1.14 ± 0.22 | 0.162 | 1.000 | 0.361 | 0.251 | 0.119 |
| Aver hypo duration tertile | 1.12 ± 0.23 | 1.13 ± 0.23 | 1.13 ± 0.22 | 0.501 | 0.818 | 1.000 | 1.000 | 0.359 |
| WASO tertile | 1.12 ± 0.21 | 1.13 ± 0.22 | 1.12 ± 0.24 | 0.447 | 0.662 | 1.000 | 1.000 | 0.746 |
| Arousal index | 1.12 ± 0.22 | 1.13 ± 0.23 | 1.13 ± 0.22 | 0.630 | 1.000 | 1.000 | 1.000 | 0.640 |
| PAC (median, IQR) | ||||||||
| AHI tertile | 13.1 (9.0,18.9) | 13.3 (9.2,19.8) | 14.2 (9.6,19.6) | 0.435 | 0.512 | 0.555 | 0.198 | / |
| AI tertile | 13.0 (8.9,18.9) | 13.0 (8.8,19.1) | 14.5 (10.1,19.7) | 0.032 | 0.270 | 0.027 | 0.053 | / |
| HI tertile | 13.1 (9.1,18.5) | 13.9 (9.4,20.1) | 13.6 (9.1,19.6) | 0.250 | 0.114 | 0.972 | 0.126 | / |
| LSaO2 tertile | 12.9 (8.7,19.0) | 13.7 (9.5,19.7) | 14.1 (10.1,19.6) | 0.046 | 0.806 | 0.016 | 0.068 | / |
| MSaO2 tertile | 13.2 (9.3,18.8) | 13.4 (9.1,19.6) | 14.3 (9.1,20.0) | 0.550 | 0.851 | 0.465 | 0.252 | / |
| T90% tertile | 13.3 (9.1,19.1) | 13.2 (9.2,19.7) | 13.9 (9.1,19.5) | 0.731 | 0.628 | 0.548 | 0.628 | / |
| ODI ≥3% tertile | 13.3 (9.1,19.8) | 13.3 (9.1,19.0) | 13.8 (9.3,19.6) | 0.764 | 0.832 | 0.795 | 0.952 | / |
| ODI ≥4% tertile | 13.5 (9.1,19.7) | 13.1 (9.0,19.2) | 13.9 (9.5,19.5) | 0.548 | 0.786 | 0.445 | 0.589 | / |
| Max hypo duration tertile | 13.5 (8.9,19.6) | 13.3 (9.0,19.7) | 13.7 (9.9,19.5) | 0.198 | 0.856 | 0.140 | 0.098 | / |
| Aver hypo duration tertile | 13.5 (8.7,19.5) | 13.4 (9.1,19.6) | 13.6 (9.9,19.5) | 0.054 | 0.315 | 0.246 | 0.011 | / |
| WASO | 13.4 (9.2,19.0) | 13.9 (9.5,20.1) | 13.2 (8.9,19.2) | 0.726 | 0.662 | 0.428 | 0.758 | / |
| Arousal index | 13.5 (9.2,19.0) | 13.6 (9.5,19.8) | 13.3 (8.9,19.5) | 0.528 | 0.625 | 0.465 | 0.338 | / |
PAC, plasma aldosterone concentration; AHI, apnea hypopnea index; AI, apnea index; HI, hypopnea index; LSaO2, lowest saturation of oxygen; MSaO2, mean saturation of oxygen; T90, time spent with oxygen saturation <90%; ODI, Oxygen Desaturation Index; hypo, hypoventilation; WASO, wake after sleep onset p, for among group comparison; p1, for T1 vs. T2 comparison; P2, for T1 vs. T3 comparison; P3, for T2 vs. T3 comparison.