Table 4.
Untreated hypertension | Normotension | |||||
---|---|---|---|---|---|---|
Non-OSA | OSA | p | Non-OSA | OSA | p | |
N | 3,775 | 2,642 | 15,951 | 3,000 | ||
Gender, men, n,% | 1,771 (46.9) | 2,059 (77.9) | <0.001 | 5,379 (33.7) | 2,449 (81.6) | <0.001 |
Women,n,% | 2,004 (53.1) | 583 (22.1) | 10,572 (66.3) | 551 (18.4) | ||
Age (years) | 49.0 (25.0,75.0) | 58.0 (47.0,66.0) | <0.001 | 41.0 (32.0,49.0) | 56.0 (40.0,56.0) | <0.001 |
<45 years (n,%) | 1,177 (31.2) | 538 (20.4) | <0.001 | 9,469 (59.4) | 953 (31.8) | <0.001 |
45–60 years (n,%) | 1,910 (50.6) | 935 (35.4) | 5,576 (35.0) | 1,068 (35.6) | ||
≥60 years (n,%) | 688 (18.2) | 1,169 (44.2) | 906 (5.7) | 979 (32.6) | ||
Education <9 years (n,%) | 2,926 (78.2) | 1,906 (74.8) | 0.003 | 10,400 (66.2) | 1,965 (67.3) | 0.039 |
≥9 years | 814 (21.8) | 640 (25.1) | 5,320 (33.8) | 954 (32.7) | ||
Cigarette use (yes, n,%) | 999 (26.6) | 925 (36.4) | <0.001 | 3,263 (20.5) | 1,361 (46.8) | <0.001 |
Alcohol intake (yes, n,%) | 1,267 (33.8) | 1,269 (50.1) | <0.001 | 4,002 (25.2) | 1,517 (52.2) | <0.001 |
CVD (n,%) | 90 (2.4) | 107 (4.0) | <0.001 | 194 (1.2) | 97 (3.2) | <0.001 |
Neck circumference (cm) | 35.4 (33.4,37.5) | 40.1 (37.4,42.0) | <0.001 | 34.2 (32.2,36.5) | 40.0 (37.6,42.1) | <0.001 |
Body mass index (kg/m2) | 24.9 (23.0,27.5) | 29.1 (26.7,31.8) | <0.001 | 23.8 (21.6,26.2) | 28.2 (26.1,30.9) | <0.001 |
AC (cm) | 88.3 (82.0,94.6) | 100.0 (93.6,106.5) | <0.001 | 83.4 (76.8,90.4) | 97.8 (92.0,104.0) | <0.001 |
Abdominal obesity (n,%) | 2,050 (54.4) | 2,266 (87.7) | <0.001 | 5,869 (37.1) | 2,485 (83.8) | <0.001 |
Systolic BP (mmHg) | 143.0 (134.0,152.0) | 146.0 (138.0,158.0) | <0.001 | 115.0 (107.0,123.0) | 122.0 (115.0,130.0) | <0.001 |
Diastolic BP (mmHg) | 91.0 (85.0,96.0) | 92.0 (86.0,98.0) | <0.001 | 74.0 (69.0,80.0) | 78.0 (70.0,82.0) | <0.001 |
FPG (mmol/L) | 5.31 (4.84,5.89) | 5.53 (5.00,6.30) | <0.001 | 5.16 (4.71,5.64) | 5.41 (4.90,6.06) | <0.001 |
ALT (U/L) | 22.0 (16.0,29.5) | 23.0 (17.0,31.0) | <0.001 | 19.0 (15.0,26.0) | 22.0 (17.0,30.0) | <0.001 |
AST (U/L) | 22.0 (19.0,27.0) | 22.0 (18.0,28.0) | <0.001 | 21.0 (17.0,25.0) | 22.0 (18.0,26.0) | 0.896 |
TC (mmol/L) | 4.90 (4.20,5.70) | 5.00 (4.30,5.70) | <0.001 | 4.50 (3.88,5.30) | 4.80 (4.10,5.60) | <0.001 |
TG (mmol/L) | 1.24 (0.90,1.80) | 1.48 (1.00,2.17) | <0.001 | 1.10 (0.80,1.60) | 1.40 (1.00,2.00) | <0.001 |
Serum Cr (mmol/l) | 69.0 (58.7,79.9) | 72.7 (61.2,84.9) | <0.001 | 67.6 (56.8,79.0) | 72.0 (61.9,84.0) | <0.001 |
No-SAS score | 4.0 (2.0,6.0) | 11.0 (9.0,11.0) | <0.001 | 2.0 (0.0,5.0) | 9.0 (9.0,11.0) | <0.001 |
OSA, obstructive sleep apnea; CVD, cardiovascular disease; AC, abdominal circumference; BP, blood pressure; FPG, fasting plasma glucose; TC, total cholesterol; TG, triglyceride; Cr, creatinine; ALT, alanine aminotransferase; AST, aspartate aminotransferase.