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. 2023 Jan 16;13:1016804. doi: 10.3389/fendo.2022.1016804

Table 5.

Comparison of PAC and log PAC between total, men, and women participants with and without OSA by presence of hypertension and by age in community-based data.

Untreated hypertension Normotension
Non-OSA OSA P Non-OSA OSA P
N 3,775 2,642 15,951 3,000
PAC (median, interquartile range)
Men 12.2 (8.7,17.5) 13.4 (9.3,19.2) <0.001 13.0 (9.2,18.4) 14.4 (10.1,20.4) <0.001
<45 years 12.8 (9.1,18.4) 14.0 (9.5,20.0) 0.025 12.9 (9.1,18.4) 15.6 (10.6,21.0) <0.001
45–60 years 12.2 (8.6,17.4) 14.0 (9.6,20.0) <0.001 13.2 (9.3,18.5) 14.9 (10.3,21.1) <0.001
≥60 years 10.3 (7.9,15.8) 12.5 (8.9,17.3) <0.001 12.7 (9.1,17.5) 13.0 (9.4,18.2) 0.403
Women 15.0 (10.8,20.9) 14.2 (10.5,19.7) 0.010 16.0 (11.2,23.1) 14.0 (10.6,18.9) <0.001
<51 years 17.3 (12.2,22.8) 16.3 (11.4,23.6) 0.007 16.6 (11.5,24.1) 17.8 (11.7,23.4) 0.841
≥51 years 14.6 (10.7,20.3) 14.10 (10.5,19.3) <0.001 14.3 (10.7,19.9) 14.0 (10.4,18.5) 0.061
Log plasma aldosterone concentration (mean ± standard deviation)
Men 2.09 ± 0.20 2.13 ± 0.20 <0.001 2.12 ± 0.20 2.16 ± 0.20 <0.001
<45 years 2.11 ± 0.20 2.14 ± 0.20 0.043 2.12 ± 0.20 2.18 ± 0.20 <0.001
45-60 years 2.09 ± 0.20 2.15 ± 0.20 <0.001 2.12 ± 0.20 2.17 ± 0.20 <0.001
≥60 years 2.05 ± 0.20 2.10 ± 0.19 0.001 2.11 ± 0.20 2.13 ± 0.20 0.362
Women 2.18 ± 0.20 2.17 ± 0.20 0.015 2.22 ± 0.23 2.16 ± 0.19 <0.001
<51 years 2.23 ± 0.23 2.20 ± 0.20 0.001 2.23 ± 0.23 2.23 ± 0.18 0.915
≥51 years 2.12 ± 0.18 2.17 ± 0.19 <0.001 2.16 ± 0.19 2.15 ± 0.19 0.043

PAC, plasma aldosterone concentration.