Table 5.
Untreated hypertension | Normotension | |||||
---|---|---|---|---|---|---|
Non-OSA | OSA | P | Non-OSA | OSA | P | |
N | 3,775 | 2,642 | 15,951 | 3,000 | ||
PAC (median, interquartile range) | ||||||
Men | 12.2 (8.7,17.5) | 13.4 (9.3,19.2) | <0.001 | 13.0 (9.2,18.4) | 14.4 (10.1,20.4) | <0.001 |
<45 years | 12.8 (9.1,18.4) | 14.0 (9.5,20.0) | 0.025 | 12.9 (9.1,18.4) | 15.6 (10.6,21.0) | <0.001 |
45–60 years | 12.2 (8.6,17.4) | 14.0 (9.6,20.0) | <0.001 | 13.2 (9.3,18.5) | 14.9 (10.3,21.1) | <0.001 |
≥60 years | 10.3 (7.9,15.8) | 12.5 (8.9,17.3) | <0.001 | 12.7 (9.1,17.5) | 13.0 (9.4,18.2) | 0.403 |
Women | 15.0 (10.8,20.9) | 14.2 (10.5,19.7) | 0.010 | 16.0 (11.2,23.1) | 14.0 (10.6,18.9) | <0.001 |
<51 years | 17.3 (12.2,22.8) | 16.3 (11.4,23.6) | 0.007 | 16.6 (11.5,24.1) | 17.8 (11.7,23.4) | 0.841 |
≥51 years | 14.6 (10.7,20.3) | 14.10 (10.5,19.3) | <0.001 | 14.3 (10.7,19.9) | 14.0 (10.4,18.5) | 0.061 |
Log plasma aldosterone concentration (mean ± standard deviation) | ||||||
Men | 2.09 ± 0.20 | 2.13 ± 0.20 | <0.001 | 2.12 ± 0.20 | 2.16 ± 0.20 | <0.001 |
<45 years | 2.11 ± 0.20 | 2.14 ± 0.20 | 0.043 | 2.12 ± 0.20 | 2.18 ± 0.20 | <0.001 |
45-60 years | 2.09 ± 0.20 | 2.15 ± 0.20 | <0.001 | 2.12 ± 0.20 | 2.17 ± 0.20 | <0.001 |
≥60 years | 2.05 ± 0.20 | 2.10 ± 0.19 | 0.001 | 2.11 ± 0.20 | 2.13 ± 0.20 | 0.362 |
Women | 2.18 ± 0.20 | 2.17 ± 0.20 | 0.015 | 2.22 ± 0.23 | 2.16 ± 0.19 | <0.001 |
<51 years | 2.23 ± 0.23 | 2.20 ± 0.20 | 0.001 | 2.23 ± 0.23 | 2.23 ± 0.18 | 0.915 |
≥51 years | 2.12 ± 0.18 | 2.17 ± 0.19 | <0.001 | 2.16 ± 0.19 | 2.15 ± 0.19 | 0.043 |
PAC, plasma aldosterone concentration.