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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: J Neurosci Methods. 2022 Dec 5;385:109761. doi: 10.1016/j.jneumeth.2022.109761

Table 2.

Theoretical percent error of different recording systems.

Variable RVr(Ω) Re1+Re2(Ω) Rbs(Ω) err 1 err 2 err total
Tissue/channel resistance Rbs 107 105 102 −0.001% −0.990% −0.991%
Tissue/channel resistance Rbs 107 105 105 −0.980% −0.990% −0.991%
Tissue/channel resistance Rbs 107 105 108 −90.8% −0.990% −91.8%
Electrode resistance Re1+Re2 107 102 102 −0.001% −0.001% −0.002%
Electrode resistance Re1+Re2 107 105 102 −0.001% −0.990% −0.991%
Electrode resistance Re1+Re2 107 108 102 −10−4% −90.9% −90.9%
Voltmeter resistance RVr 104 105 102 −0.091% −90.9% −91.0%
Voltmeter resistance RVr 107 105 102 −0.001% −0.990% −0.991%
Voltmeter resistance RVr 109 105 102 −10−6% −0.001% −0.001%
n/a (this work) 107 1.4 × 105 7.4 × 102 −1.39% −0.007% −1.38%

The first error is due to too much current rerouted into the recording system. err1=RbsRbs+Re1+Re2+RVr.

The second error is due to significant voltage drop across the recording electrodes instead of voltmeter. err2=Re1+Re2(Re1+Re2)RVr.

errtotal=err1+err2.

Polarizable electrodes result in additional electrochemical reactions at the interface and is therefore excluded from this estimation.