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. 2023 Jan 16;13:1098012. doi: 10.3389/fendo.2022.1098012

Table 2.

Univariate and multivariate COX regression analysis of incident hypertension.

Univariate Multivariate
HR (95% CI) P value HR (95% CI) P value
Age 1.025 (1.020, 1.029) < 0.001 1.022 (1.017, 1.027) < 0.001
Male 1.135 (1.021, 1.263) 0.019 1.081 (0.914, 1.279) 0.361
Higher than high school 0.737 (0.606, 0.897) 0.002 0.809 (0.662, 0.989) 0.038
Married 0.964 (0.810, 1.148) 0.684 0.925 (0.774, 1.105) 0.389
Smoking status: Never 0.888 (0.791, 0.997) 0.045 0.941 (0.811, 1.091) 0.420
Drinking status: No drinking 0.776 (0.657, 0.917) 0.003 0.899 (0.743, 1.087) 0.270
Diabetes 1.390 (1.168, 1.655) < 0.001 0.889 (0.696, 1.135) 0.346
Hypoglycemic drugs 1.712 (1.161, 2.523) 0.007 1.151 (0.738, 1.796) 0.534
BMI 1.048 (1.031, 1.066) < 0.001 1.039 (1.020, 1.058) < 0.001
SBP 1.032 (1.026, 1.038) < 0.001 1.010 (1.004, 1.016) 0.001
DBP 1.035 (1.026, 1.045) < 0.001 1.009 (0.999, 1.018) 0.064
TG 1.056 (1.022, 1.091) 0.001 1.027 (0.972, 1.084) 0.349
TC 1.115 (1.058, 1.176) < 0.001 0.982 (0.874, 1.103) 0.754
LDL−C 1.085 (1.030, 1.143) 0.002 0.992 (0.877, 1.123) 0.902
HDL−C 0.971 (0.864, 1.092) 0.626
ApoA1 1.077 (0.961, 1.208) 0.203
ApoB 1.610 (1.312, 1.976) < 0.001 1.133 (0.720, 1.783) 0.588
CR 1.002 (1.000, 1.004) 0.033 1.000 (0.996, 1.004) 0.987
Uric acid 1.001 (1.000, 1.001) 0.007 1.000 (0.999, 1.001) 0.840
FPG 1.075 (1.041, 1.111) < 0.001 0.984 (0.929, 1.043) 0.590
Hs-CRP 1.010 (1.004, 1.016) 0.002 1.005 (0.997, 1.012) 0.208
HbA1c 1.161 (1.105, 1.221) < 0.001 1.102 (1.006, 1.206) 0.037

BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglycerides; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; CR, creatinine; FPG, fasting plasma glucose; Hs-CRP, high-sensitivity C-reactive protein; HbA1c, hemoglobin A1c; HR, hazard ratio; CI, confidence interval.